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Academic Qualifications
1. Post Doctoral
Level Research at the University of Glasgow, UK (1986-1988).
2. Doctor of Philosophy in Immunology (1986), from the Department
of Immunology, University of
Glasgow, UK.
3. Master of Science in Biochemistry (1980), from the Department of
Biochemistry, University of
Dhaka. Secured the first position in the first class.
4. Bachelor of Science with Honors in Biochemistry (1978), from the
Department of Biochemistry,
University of Dhaka. Secured the first position in the first class.
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Corresponding
Address
Professor
Laila N. Islam, Citizenship: Bangladeshi by birth
Department of Biochemistry and Molecular Biology, University of Dhaka,
Dhaka-1000, Bangladesh.
Telephone: +880-2- 9661920-73 Ext. 7637 (Work); +880-2-8625303
(Res.)
Fax: 880-2-8615583.
E-mail: lailanislam@yahoo.com
Awards and
Honors received
1. Awarded the
Commonwealth Scholarship (1983) for Ph.D. at the University of Glasgow,
UK.
2. Awarded The Dhaka University Book Prize (twice) for obtaining the
first position at the M. Sc. final and B. Sc. Honors examinations
held in 1980 and 1978, respectively.
3. Honored with the 'Chancellor Award' for securing the first position
at the B.Sc. Honors examination held in 1978.
4. Awarded 'Board Scholarship' with free tuition fees on the basis
of marks obtained in the Secondary and Higher Secondary examinations
of 1971 and 1973, respectively.
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Professional
Appointments and Fellowship
1. Worked as a
Scientific Officer at the Bangladesh Rice Research Institute, Joydevpur,
Dhaka (March 1981 to April 1982).
2. Joined the Department of Biochemistry, University of Dhaka as a
Lecturer (April 1982 to November 1988).
3. Awarded the Commonwealth Scholarship for Ph.D. at the University
of Glasgow, UK (October
1983 to September 1986), and worked on 'Chemoattractant-induced polarization
and locomotion of human blood leukocytes'.
4. Post Doctoral Research Fellowship to work with the lymphocytes
of Chronic Lymphocytic Leukemia patients, at the University of Glasgow,
UK, on a Leukemia Research Fund project (November 1986 to October
1988).
5. Assistant Professor, Department of Biochemistry, University of
Dhaka (November 1988 to
September 1990).
6. Part-Time teaching at the Department of Microbiology, University
of Dhaka (1990 to 1991).
7. Worked as a Consultant at the Immunology Laboratory, under the
Laboratory Sciences Division, International
Center for Diarrheal Disease Research, Bangladesh (ICDDR,B), for
two years and studied on the immune response in monkeys with experimental
shigellosis, children with shigellosis, and with acute diarrhea (1990
to1992).
8. Associate Professor, Department of Biochemistry, University of
Dhaka (September 1990 to
July 1994).
9. Professor, Department of Biochemistry, University of Dhaka (July
1994 till to date).
10. Chairperson, Department of Biochemistry and Molecular Biology,
University of Dhaka
(November 2003- for 3 years).
11. Director, Biotechnology Research
Center, University of Dhaka (December 2005-till to date).
12. Founder Chairman,
DU-BMB TRUST, Department of Biochemistry and Molecular Biology,
University of Dhaka, Bangladesh
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Research Areas
Working in the
fields of Cellular and Clinical Immunology, and Clinical and Nutritional
Biochemistry for the last 22 years. Worked on the functional activities
of neutrophils, lymphocytes, and monocytes in response to chemotactic
factors, bacterial antigens, and mitogens. Studied the functions of
neutrophils from monkeys with experimental shigellosis, and children
with shigellsis at the ICDDR,B; and from patients with diabetes mellitus.
Also studied the biochemical and immunological markers in patients
with hepatitis B and C virus infections. At present, working on the
biochemical and immunological aspects of human arsenic toxicity.
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Current Research
Interest
1. Evaluation
of biochemical and immunological changes in chronic arsenic poisoning
among
Bangladeshi patients.
2. Working on the effects of nutritional factors on the immune response
in patients suffering from drinking water arsenic toxicity.
3. Study of complement mediated bactericidal activity in patients
with diabetes mellitus.
4. Effect of environmental pollution on the level of serum IgE and
its relationship with some
allergic diseases.
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Principal Investigator
of Research Projects
1. 'Study of the
in vitro and in vivo Activation of Granulocytes by Shigela dysenteriae
Type 1'
funded by the Dhaka University Biotechnology Research Center (1990-1991).
2. Small items of equipment and reagents for research works were obtained
from the Islamic
Educational, Scientific and Cultural Organization (ISESCO, 1992).
3. 'Immunological Investigations on Arsenic Toxicity in Human' funded
by the Ministry of Science
and Information & Communication Technology, Government of the
People's Republic of
Bangladesh (2000-2001).
4. 'Biochemical Changes in the Serum of Arsenicosis Patients', funded
by the Ministry of
Science and Information & Communication Technology, Government
of the People's Republic
of Bangladesh (2002-2003).
5. 'Biochemical Investigations on Arsenic Toxicity in Human' funded
by the University
Grants Commission of Bangladesh (2001-2002/2004).
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Research Supervision
Research works
of 22 M.Sc./MS thesis students and 2 M.Phil. students have so far
been supervised all whom obtained their respective degrees. The research
works of two MS and two M. Phil. students are currently under supervision.
Conference
and Symposium Attended
1. Participated
the Annual Conference and Grant holders' meeting of the Leukaemia
Research
Fund, held in London, UK (November 1987).
2. Participated the 8th FAOB Symposium on 'Biochemistry in Health
and Diseases' organized
by the Bangladesh Biochemical Society and the Federation of Asian
and Oceanion Biochemistry
(FAOB) held in Dhaka, and presented a paper on 'Polarization of Human
Neutrophils to
Shigella dysenteriae Type 1 Antigens' (June 1991).
3. Attended a practical course in 'Techniques in Molecular and Cellular
Immunology' organized by
the International Center for Genetic Engineering and Biotechnology
(ICGEB), New Delhi, India
(November 2000).
Organizer
1. Served as the
Executive Committee Member, Bangladesh Association, Scotland (1986-1988).
2. Organized different cultural functions of the expatriate Bangladeshis
living in Scotland.
3. Served as organizer and had been the Editor of the Annual Magazine
'Reflection'
published by the Bangladesh Association, Scotland (1986-1987).
4. Had been the organizer of the 'Book Prize' donated to the department
of Biochemistry,
University of Dhaka, by the British Society for Immunology in memory
of Professor
Robert J. White (1988).
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Association
with Journals
Editorial Board
Member of Bangladesh Journal of Microbiology (1997 till to date).
Editorial Board Member of Bangladesh Journal of Biochemistry (1998
till to date).
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Reviewer
Reviewed Scientific
Articles published in the following Journals:
1. Bangladesh Journal of Biochemistry
2. Dhaka University Journal of Biological Sciences
3. Bangladesh Journal of Microbiology
4. Bangladesh Journal of Nutrition
5. Bangladesh Journal of Scientific and Industrial Research
6. Bangladesh Journal of Science & Technology
--Reviewed
Scientific Projects submitted for funding by:
1. University
Grants Commission of Bangladesh.
2. The Dhaka University Biotechnology Research Center.
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Member
1. National Drug
Policy Review Committee, Ministry of Health and Family Welfare, Government
of the People's Republic of Bangladesh.
2. National Technical Committee on Medical Biotechnology, Ministry
of Health and Family
Welfare, Government of the People's Republic of Bangladesh.
3. Prevention of the Use of Toxic Chemicals in Foods, Fruits and Vegetables,
Ministry of Law,
Justice and Parliamentary Affairs, Government of the People's Republic
of Bangladesh.
4. Finding Suitable Alternative to Polythene Shopping Bags, Ministry
of Environment and Forest,
Government of the People's Republic of Bangladesh.
5. Governing Body, Bangladesh Institute of Child and Health (2002
till to date).
6. Member, Dhaka University Senate (2005 till to date).
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Society Membership
1. British Society
for Immunology (ex-Member).
2. Bangladesh Society for Biochemistry
and Molecular Biology (Life member).
3. Bangladesh Nutrition Society (Life member).
4. Bangladesh Association for the Advancement of Science (Life member).
5. Bangladesh Society for Immunology (Founder member)
- Served the Bangladesh
Society for Biochemistry and Molecular Biology in different capacities
(1995 till to date)
· Executive Committee Member, Bangladesh Society of Microbiologists
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Language
Bangla: Mother
tongue
English: Excellent
Major Publications
1. N. H. Khan,
Laila Noor, M. Begum and M. Rahman (1981) Studies on the antibacterial
activity of some indigenous plant extracts. Bangladesh J. Biol. Sci.
10, 31-38.
2. Laila Noor and N. H. Khan (1982) Studies on ninhydrin positive
compounds present in some seeds. Dhaka Univ. Studies, Part B, 30,
99-105.
3. Laila N. Islam, I. C. McKay and P. C. Wilkinson (1985) The
use of collagen or fibrin gels for the assay of human neutrophil chemotaxis.
J Immunol. Meth. 85, 137-151.
4. Laila N. Islam and P.C. Wilkinson (1988) Chemotactic factor-induced
polarization, receptor redistribution, and locomotion of human blood
monocytes. Immunology, 64, 501-507.
5. P.C. Wilkinson, Laila N. Islam, D. Sinclair and J. H. Dagg
(1988) The defect of lymphocyte locomotion in chronic lymphocytic
leukaemia: studies of polarization and growth dependent locomotion.
Clin. Exp. Immunol. 71, 497-501.
6. P.C. Wilkinson, J. M. Lackie, W. S. Haston and Laila N. Islam
(1988) Effects of phorbol esters on shape and locomotion of human
blood lymphocytes. J. Cell Sci. 90, 645-655.
7. Laila N. Islam and P.C. Wilkinson (1989) Evaluation of methods
for isolating human peripheral blood monocytes: Studies on chemotactic
locomotion and other functional characteristics. J. Immunol. Meth.
121, 75-84.
8. P.C. Wilkinson and Laila N. Islam (1989) Recombinant IL-4
and IFN-gamma active locomotor capacity in human B-lymphocytes. Immunology,
67, 237-243.
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9. M. S. Islam,
N. Saha and Laila N. Islam (1992) Neutralization of hemagglutinating
activity of Shigella flexneri 2a by a specific monoclonal antibody.
Dhaka Univ. J. Biol. Sci. 1, 123-126.
10. Laila N. Islam and P.C. Wilkinson (1992) Restoration with
phorbol ester of a locomotor defect in human leukaemic lymphocytes:
A visual study of chronic lymphocytic leukaemia cells. Invasion Metastasis
12, 47-56.
11. Laila N. Islam and M. K. Hossain (1993) Polarization of
human neutrophils to antigens of Shigella dysenteriae type 1. Dhaka
Univ. J. Biol. Sci. 2, 201-208.
12. Laila N. Islam (1994) Study on the morphological change
and phagocytic activity of human monocytes in culture. Dhaka Univ.
J. Biol. Sci. 3, 49-58.
13. Laila N. Islam, A. Ferdous, T. Azim, F. Qadri, A. S. M.
H. Rahman, M. S. Islam and S. Tzipori (1994) Peripheral blood granulocytes
and mononuclear cell responses in monkeys with experimental shigellosis.
J. Diarrhoeal Dis. Res. 12, 97-102.
14. M. S. Islam, Laila N. Islam and W. H. Stimson (1994) Direct
enzyme-linked immunosorbent assay for identification of Shigella flexneri.
Bangladesh J. Sci. Res. 12, 35-40.
15. T. Azim, Laila N. Islam, R. C. Halder, J. Hamadani, N.
Khanum, M. S. Sarker, M. A. Salam and M. J. Albert (1995) Peripheral
blood neutrophil responses in children with shigellosis. Clin. Diag.
Lab. Immunol. 2, 616-622.
16. A. Ferdous and Laila N. Islam (1995) Total white blood
cell count and phagocytic activity of the neutrophils in monkeys with
experimental shigellosis. Bangladesh J. Biochem. 1, 23-32.
17. Laila N. Islam, Kazi Mokim Ahmed and Shahnaj Shammy (1997)
Modulation of human neutrophil functions by Vibrio cholerae lipopolysaccharide.
Bangladesh J. Biochem. 3, 75-86.
18. Laila N. Islam (1998) Human blood monocyte invasion and
chemokinesis through collagen matrices. Dhaka Univ. J. Biol. Sci.
7, 9-22.
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19. Laila N
Islam, U. K. Chowdhury, A. K. Roy, M. K. Hossain, S. Shammy and
M. S. Islam (1998) Human neutrophil responses to LPS, OMP and Toxin
of Shigella dysenteriae type 1, and comparison with responses to FMLP.
Dhaka Univ. J. Biol. Sci. 7, 99-112.
20. Laila N. Islam, K. Saiful Islam, M. Enamul Kabir, M. Sazzad
Hossain, A. H. M. Nurun Nabi and N. G. Banik (2000) Impaired neutrophil
function in diabetes mellitus. Bangladesh J. Biochem. 6, 45-59.
21. Tasnim Azim, Laila N. Islam, M. S. Sarker, S. M. Ahmad,
Jena D. Hamadani, S. M. Faruque and M. A. Salam (2000) Immune response
of Bangladeshi children with acute diarrhoea who subsequently have
persistent diarrhoea. J. Pediatric Gastroenterol. Nutr. 31, 528-535.
22. A.H.M. Nurun Nabi and Laila N. Islam (2001) Study of the
functions of human neutrophils in response to Klebsiella pneumoniae
LPS. Dhaka Univ. J. Biol. Sci. 10, 59-68.
23. Kajla Seheli, Hasna Yusuf Kanta and Laila N. Islam (2002)
Activation by mitogens and endotoxins of human peripheral blood lymphocytes:
morphological polarization, locomotion and cell type study. Dhaka
Univ. J. Biol. Sci. 11, 49-58.
24. K. N. Hasan, M. A. K. Rumi, M. A. Hasanat, M.G. Azam, S. Ahmed,
M. A. Salam, Laila N. Islam and M. S. Hassan (2002) Chronic
carriers of hepatitis B virus in Bangladesh: A comparative analysis
of HVB-DNA, HBeAg/Anti-HBe, and liver function tests. Southeast Asian
J. Trop. Med. Public Health. 33, 110-117.
25. Laila N. Islam, A. H. M. Nurun Nabi, K. Mokim Ahmed and
Novera Sultana (2002) Endotoxins of enteric pathogens are chemotactic
factors for human neutrophils. J. Biochem. Mol. Biol. 35, 482-487.
(Available online at http://www.jbmb.or.kr/ )
26. ASM Jubayer, Laila N. Islam, M. Zakaria Shamim and AFM
Abdul Hye (2003) Diagnosis and follow up study of serum enzymes in
patients with Hepatitis C virus infection.Bangladesh J. Med.Sci.,
9: 22 - 27.
27. Laila N. Islam and A. H. M. Nurun Nabi (2003) Endotoxins
of enteric pathogens modulate the functions of human neutrophils and
lymphocytes. J. Biochem. Mol. Biol. 36, 565-571. (Available online
at http://www.jbmb.or.kr/)
28. Laila N.Islam, A. H. M. Nurun Nabi, M. Mahfuzur Rahman,
Monsur A.
Khan, and Azizul I. Kazi,
(2004) Association
of clinical complications with nutritional status and the prevalence
of
leukopenia among
arsenic patients in Bangladesh. Int. J. Environ. Res. Public Health,
1, 74-82
29. A. H. M. Nurun Nabi, Laila N. Islam,
M. Mahfuzur Rahman and Kazal Boron Biswas (2005) Polymorphonuclear
neutrophil dysfunctions in streptozotocin-induced type 1 diabetic
rats. J. Biochem. Mol. Biol. 38: 661-667.
30. A. H. M. Nurun Nabi, M. Mahfuzur
Rahman and Laila N. Islam (2005) Evaluation of Biochemical
changes in chronic arsenic poisoning among Bangladeshi patients. Int.
J. Environ. Res. Public Health, 2, 385-393.
31. Laila
N. Islam,
Mahmud Hossain and M. Shamim H. Zahid (2006) Complement
mediated bactericidal activity and humoral immune response in type 2
diabetes mellitus. Int. J. Diabetes Metab, 14, 92-97.
32. Laila N. Islam, A. H. M.
Nurun Nabi, M. Mahfuzur Rahman and M. Shamim H. Zahid (2007)
Association of respiratory complications and elevated serum
immunoglobulins with drinking water arsenic toxicity in human. J.
Environ. Sci. Health Part A, 42: 1807-1814.
33. M. Safiullah Sarker, Mustafizur Rahman, David Yirrell, Eileen
Campbell, A. S. M. Matiur Rahman, Laila N.Islam and Tasnim Azim
(2008) Molecular evidence for polyphylectic origin of human
immunodeficiency virus type 1 subtype C in Bangladesh. Virus Res.
135: 89-94.
Chapter in
Book
Laila N. Islam
(2002) Infection and Inflammatory Responses in Diabetes. In: New Vistas
in Type 2 Diabetes (ed. RJ Das) Vol.1, pp 290-318. Published by: Research
Society for the Study of Diabetes in India.
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