Chairman::Prof. Ishtiaq Mahmud, Department of Biochemistry and Molecular Biology


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Name: Prof. Ishtiaq Mahmud Personal/Contact address Academic Qualification Professional Appointments and Fellowship Name of Referees List of Publications
Professional Meetings, Symposia, and Congress Attended Society Membership

Personal/Contact address
Name: Ishtiaq Mahmud Date of Birth: January 15, 1951 Nationality: Bangladeshi By birth Professor Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka-1000 Bangladesh. Tel. 880-2-8914374 (Res.), 880-2-9661920-73-Ext.7635(Off.) Fax: 880-2-8615583, 888474, e-mail: ishtiaq51@yahoo.com Back to top
Academic Qualification
B. Sc. (Honors) in Biochemistry: University of Dhaka, 1967-1970, Dhaka, Bangladesh M. Sc. in Biochemistry: University of Dhaka, 1970-1973, Dhaka, Bangladesh Diploma in Microbiology: Tokyo University, 1974-1975, Tokyo, Japan Ph.D. in Biochemistry: Chiba University, 1977-1981, Chiba, Japan Back to top
Professional Appointments and Fellowship
1. Research Fellow, Institute of Nutrition and Food Sciences, University of Dhaka, Dhaka, Bangladesh 4/73-10/74. 2. UNESCO Fellowship in Microbiology, Faculty of Agriculture, Tokyo University, Tokyo, Japan 10/74-9/75. 3. Lecturer, Institute of Nutrition and Food Sciences, , University of Dhaka, Dhaka, Bangladesh 9/75-1/76. 4. Research Fellow, Department of Biochemistry, Chiba University, School of Medicine, Chiba, Japan 1/76-3/77 5. Post Doctoral Fellow, Department of Pharmacology, Minnesota University, Minnnesota U.S.A. 8/81-5/82. 6. Post Doctoral Fellow. Institute of Pharmacology and Metabolism, Syntex Research, California, U.S.A. 7/82-1/84. 7. Post Doctoral Research Associate. Institute of Biological Sciences, Syntex Research, California, U.S.A. 2/84-1/86. 8. Assistant Professor, Department of Biochemistry, Faculty of Biological Sciences, University of Dhaka, Dhaka, Bangladesh 1/87-3-90. 9. Visiting Scientist, Department of Biochemistry. Tokushima University School of Medicine. Tokushima, Japan 4/90-9/90. 10. Alexander Von Humboldt Research Fellowship, Faculty of Biological Sciences, University of Konstanz, Germany.1/91-12/91. 11. Associate Professor, Department of Biochemistry, Faculty of Biological Sciences, University of Dhaka, Dhaka, Bangladesh 3/90-7/94. 12. Visiting Professor, Department of Biochemistry, Tokushima University School of Medicine. Tokushima, Japan 8/96-3/97. Back to top
Name of Referees
1. Professor V. Ullrich, Faculty of Biology, University of Konstanz, Postfach 5560. W-7750 Konstanz, Germany. 2. Prof. S. Yamamoto. Department of Biochemistry, Tokushima University School of Medicine. Tokushima, Japan. 3. Professor Y. Miura, 1-8-17, Nishikata, Bunkyo-ku Tokyo 113, Japan. 4. Professor H. K. M. Yusuf, Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka-1000, Bangladesh. Back to top
List of Publications
1. Saiki, T. Mahmud, I., Matsubara, N., Taya, K., and Arima. K. Purification and some properties of NADP+-specific isocitrate dehydrogenase from an extreme thermophile Thermus flavus AT-62. In: Monograph of the Symposium on Enzymes and Proteins from Thermophilic Organism, Zurich, Switzerland (1975). 2. Mahmud, I., and Miura, Y. (1977) Protein in the food prolongs DNA synthesis in the liver of rats after starvation. J. Biochem., 82, 911-913 3. Mahmud, I., and Miura, Y. (1977) High protein diet can induce DNA synthesis in rat liver for longer period than amino acids diet. In: Monograph of First Congress of Federation of Asian and Oceanian Biochemists, Nagoya, Japan. 4. Miura Y., Fukui, N., Kanzaki, Y., Mahmud, I. (1978) Induction of ornithine decarboxylase and DNA synthesis in isolated perfused liver after partial hepatectomy. Adv. Enzyme Regul. 16, 195-203. 5. Mahmud, I., Asanagi, M., Kanzaki, Y., and Miura Y. (1978) A long-run perfusion of rat liver. In-vitro regeneration of liver. Proc. 4th Internation Symposium on Perfluorochemical Blood Substitute, Kyoto, Japan (1978). Back to top 6. Kanzaki, Y., Mahmud, I., Asanagi, M, Fukui, N., and Miura, Y. (1979) Thromboxane as possible trigger of liver regeneration. Cell. Molec. Biol. 25, 147-152. 7.Mahmud, I., Fukui, N., and Miura, Y. (1980) Arachidonic acid metabolism in normal and regeneration rat liver and hepatoma. Adv. Enzyme Reg., 18, 27-37. 8. Karimi-Tari, F., Mahmud, I., Fukui, N., and Miura, Y. (1980) Induction of ornithine decarboxylase and DNA synthesis after liver injury, Cell. Molec. Bio., 26, 647-652. 9. Mahmud, I., Asanagi, M., and Miura, Y. (1980) Biphasic increase in ornithine decarboxylase and its ralationship with thymidine kinase and DNA synthesis in liver. Biochem, Biophys., Res. Commun., 93, 661-667. 10. Mahmud, I., and Miura, Y. (1981) Effects of stimulators and inhibitors on arachidonic acid metabolism in hepatoma. Cell. Molec. Biol., 27,197-202. 11. Miura, Y., Mahmud, I., Karimi—Tari, F., Hiyama, Y., and Fukui, N. (1981) Regulation of the arachidonic cascade in normal liver and hepatoma cells. Adv. Enzyme Reg., 20, 27-35. 12. Hiyama, Y., Mahmud, I., Karimi-Tari, F., Fujita, S., Fukui, N., and Miura, Y. (1981) Platelet derived growth factor and thromboxane are necessary for liver regeneration . Cell. Molec. Biol., 27, 593-599. 13. Fuse, A., Mahmud, I., and Kuwata, T. (1982) Mechanism of stimulation by human interferon of prostaglandin synthesis in human cell lines. Cancer Res. 42.33209-3214. 14. Nagel B., Mahmud, I., Churchill, V., Whyte, M., Smith D.L., and Willis, A. L.(1984) Nicardipine and nifedipine inhibit arteriosclerosis and aortic deposition of cholesterol and triglycerides. Fed. Proc. 43(4), 843. 15. Mahmud, I., Alvarez, R. Miller, F., Nelson, J.T., Cho, D., Tokes, L.G., Smith D.L., Whyte, M.A. Willis, A.L. (1984) Properties of Prostaglandin J2 Fed. Proc. 43 (4), 980. 16. Smith D.L., Willis, A.L. and Mahmud, I. (1984) Eicosanoid effects on cell proliferation in vitro: Relevance to artriosclerosis. Prostagladins, Leukotriens and Medicine 16, 1-10. Back to top 17. Mahmud, I., Fukui, N., Miura, Y. and Brandenberger, H. (1984) Thromboxane synthesizing system in rat liver. Prostaglandins Leukotrienes and Medicine 16, 371-377. 18. Mahmud, I., Smith . D. L. Whyte, M.A., Nelson, J.T., Cho, D., Tokes, L.G., Alvarez. R., and Willis, A.L. (1984) On the identification and biological properties of prostaglandin J2. Prostaglandins Leukotriens and Medicine 16, 131-146. 19. Willis, A.L. Negel, B., Churchill, V., Whyte, M.A. Smith, D.L., Mahmud, I., and Puppione, D. (1985) Antiarteriosclerosis effects of nicardipline and nifedipine in cholesterol-fed rabbits. Arteriosclerosis 5(3), 250-255. 20. Mahmud, I., Taylor, L.A. and Krishna-Murthy, D.V., (1985) Phospholipase activities in human macrophage-like cell line U937, Fed. Proc. 44 (4), 1204. 21. Mahmud, I., and Goldberg, N.D. (1988) Enzymic-fluorometric method for the measurement of phospholipase C activity. University of Dhaka Studies, Part E 3(1) 7-14. 22. Mahmud, I., and Willis A. A.L. (1988) A new assay for studying proliferation of aortic smooth muscle cells. University of Dhaka Studies, Part E 3(1) 85-8723. 23. Mahmud, I., Pbzhitokob, M., and Willis, A.L., (1988) Nicardipine inhibits release of free fatty acids from open chest coronary occluded dog. University of Dhaka Studies, Part E 3(2) 149-152. 24. Mahmud, I., Schlarb, C., Brune, B, and Ullrich. V. (1991) Regulation of Arachidonic acid metabolism in differentiated human erythroleukemia cell line (HEL). In. Abstract of the 2nd Internatinal Conferrence on Eicosanoids and other Bioactive Lipids in Cancer, Inflammation and Radiation injuru. Berlin, Germany. 25. Mahmud, I., and Murthy, D.V.K. (1989) Induction of Phospholipase A2 activity in U937 cell line. In: Programme Abstracts of the 5th FAOB Congress, held in Seoul, Korea. 26. Mahmud, I., Suzuki, T., Yamamoto, Y., Suzuki, H., Takahashi, Y., Yoshimoto T., and Yamamoto, S. (1993) Induction of Cyclooxygenase and Suppression of 12- Lipoxygenase in human erythroleukemia cells upon phorbol ester induced differtiation. Biochimica and Biophysica Acta. 1166, 211-216. Back to top 27. Salamatullah, Q., Hossain, S., Mahmud, I., and Bashar, S.A.M.K. (1993) Dose effects of Pangas (Pangasius-pangasius) fish oil and soybean oil on serm and liver lipids in experimental hypercholesterolemic rats. University of Dhaka Journal of Biological Sciences. 2 (1), 69-67. 28. Mahmud, I., I,Yoshimoto., T., and Yamamoto , S.(1991) Induction of thromboxane formation in human erythroleukemia cells. Bangladesh Journal of Scientific research. 11(2). 243-247 29. Mahmud, I., and ullrich V. (1993) Effect of a new nonsteroidal anti-inflammatory drug in the formation of thromboxane in human platelets. Dhaka University Journal of Biological Sciences.3(1)89-92 30. Mahmud, I.,Yoshimoto, T and Yamamoto. S(1993) Induction of thromboxane synthase in human erythroleukemia cells by phorbol ester. 3(1) 17-22. Dhaka University Journal of Biological Science 31. Mahmud, I.,Yoshimoto, T. and Yamamoto. S(1993) Induction of thromboxane formation in human erythroleukemia cells, Bangladesh Journal of Scientific research. 11(2). 243-247 32. Mahmud, I., and ullrich V.(1994) Profile of a novel highly potent anti-inflammatory compound CGP 28238. Journal of Bangladesh Academy of Sciences. 18(2), 137-140 33. Mahmud, I and ullrich V.(1994) Profile of a novel anti-inflammatory compound CGP 23828. Journal of Society for Pharmaceutical Chemists.3(1),41-46 34. Mahmud, I.(1994) Induction of Prostaglandin F2 synthesis by retionic acid in human erythroleukemia (HEL) cells. (Accepted for publication in the Bangladesh Journal of Scientific Research). 35. Hossain M. Muazzem., Mohiduzzaman, M., Nahar. L., Mahmud, I., and Salamatullah, Q. (1995) Impact of diet counseling on the nutritional status of male students of Dhaka University, Dhaka University Journal of Biol. Sci, 4(1)1-6 36. Shoib Chowdhury, A. H. M., Shekhar, H. U., Quddus M.A.A.M. and Mahmud, I. (1995)Bichemical anlysis of Tenualosa ilisha (Hamilton) 21(1); 83-88. Asiatic society of Bangladesh. Back to top 37. Mahmud, I., Taylor, L.A., And Krishna-Murthy,, D.V.K. Phospholipase activities in human macrophage-like cell line U937 (in prep). 38. Mahmud, I., Taylor, L.A. and Krishna-Murthy, D.V.K. possible mechanism of induction of Phospholipase activities in human macrophase-like cell line U937 (in prep.) 39.,Mahmud, I. Schlarb, C., Brune, B., and Ullrich, V. (1991) Induction of Cyclooxygenase and thromboxane synthase in human erythrleukemia cell line (HEL)by retinoic acid. (in prep.) 40. Mahmud, I . Schlarb, C., Brune, B., and Ullrich, V. (1991) Retinoic acid induced stimulation of PGE2 in human erythroleukemia cell line(HEL).(in prep.) 41. Mahmud, I.,Ueda, N.,Yamaguchi, H., Yamashita, R., Yamamoto, S., Kanaoka, Y., Urade, Y. and Hayishi, O. (1997) Prostaglandin D synthase in human megakaryoblastic cells. J. Biol> Chem. 272, 28263-28266 42. Mahmud, I., Yoshimoto, T., Yamamoto, S.,(1995) Phorbol ester induction of cyclooxygenase and suppression of 12- lipoxygenase in human erytheoleukemia cells. Bangladesh J Sci Res 13 (1), 89-91 43.Ali, M, M, Islam, Z., Ali, M,. Rasul, MN, Farzana, t,. Faruque M, O,. Seraj Z, I,. And Mahmud, I.(1997). Relationship of glyoxalase-1 activity with regeneration potential of embryo-derived rice callus. Bangladesh J Biochem 3 (2) 87-93 44.Rahaman Mh, Zinnat R, Mahmud, I and Ali L. Pathogenesis of Platelet hyperaggregabilty in diabetes mellitus . Brochure of the 4th diabetes and endocrine conference. Dhaka, Bangladesh, December 12-13, 1998 45.Rahman S, Zaman K, Alam S, Mahmud, I . Serum polyamines as a possible biochemical marker for the diagnosis of cancer. Brochure of the 5th dibetes and Endocrine Conference. Dhaka, Bangladesh, December 2-4, 1999 46.Zinnat R, Rahman MH, Mahmud, I. Khan AK Azad and Ali L. Role of Serum Glucose and Insulin in the Pathogenesis of platelet Hyperaggregation in diabetic Subjects; Diabetologia 1999; 42 (Suppl 1): A 320. 47.Yamamoto S, Ueda N, Mahmud, I, Yamaguchi H, Yamashita r, Yamamoto K, Ishimura K, Yrade Y, Kanooka Y, Hayaishi O. Fatty acid Cyclooxygenase induction accompanied by prostaglandin D synthesis in a human megakaryoblastic cell line CMK differentiated by phorbol ester. Biofactors 2000; 11: 57-61 Back to top
Professional Meetings, Symposia, and Congress Attended
1. Attended the Annual Japanese Biochemical Society Conference from 1976 to 1980 and presented papers regularly. 2. Attended and presented papers on DNA Synthesis in rat liver in the First Congress of Federation of Asian and Oceanian Biochemists held in Nagoya, Japan (1977). 3. Attended and presented a paper on long run perfusion of rat liver in the 4th International Symposium on Perflurochemical Blood Substitute held in Kyoto, Japan (1978). 4. Attended and presented a poster on prostaglandin J2 in the FASEB meeting held in St. Louis, Missouri, USA (1984). 5. Attended and presented a poster on Phospholipase activities in U937 cell line in the FASEB meeting held in Anaheim , California, USA (1985). 6. Attended the FAOB symposium in Karachi, Pakistan with a Fellowship for young Scientists from FAOB (1987). 7. Attended the annual Japanese Biochemical Society Conference held in Osaka, Japan (1990). 8. Attended and presented a poster on arachidonate metabolism in HEL cells at the 2nd International Conference on Eicosanoids, held in Berlin, Germany (1991). Back to top
Society Membership
1. President, Japanese Universities Alumni Association in Bangladesh, (JUAAB). 2. Member, Nutritional Society of Bangladesh. 3. Member, Biochemical Society of Bangladesh. 4. Member, Society for Pharmaceutical Chemists, Bangladesh. 5. Member, Asiatic Society of Bangladesh. Back to faculty index
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Copyright© Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka-1000, Bangladesh.